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Promotion of RAD51-mediated homologous DNA pairing by BRCA1-BARD1
The tumor suppressor complex BRCA1-BARD1 functions in DNA double-strand break repair by homologous recombination. Therein, BRCA1-BARD1 facilitates the nucleolytic resection of DNA ends to generate a single-stranded template for the recruitment of another tumor suppressor complex BRCA2-PALB2 and the...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800781/ https://ncbi.nlm.nih.gov/pubmed/28976962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24060 |
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