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RAD51AP1 mediates RAD51 activity through nucleosome interaction
RAD51-associated protein 1 (RAD51AP1) is a key protein in the homologous recombination (HR) DNA repair pathway. Loss of RAD51AP1 leads to defective HR, genome instability, and telomere erosion. RAD51AP1 physically interacts with the RAD51 recombinase and promotes RAD51-mediated capture of donor DNA,...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233230/ https://ncbi.nlm.nih.gov/pubmed/34058198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100844 |
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