Promotion of RAD51-mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex

The UAF1-USP1 complex deubiquitinates FANCD2 during execution of the Fanconi anemia DNA damage response pathway. As such, UAF1 depletion results in persistent FANCD2 ubiquitination and DNA damage hypersensitivity. UAF1 deficient cells are also impaired for DNA repair by homologous recombination. Her...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Liang, Fengshan, Longerich, Simonne, Miller, Adam S., Tang, Caroline, Buzovetsky, Olga, Xiong, Yong, Maranon, David G., Wiese, Claudia, Kupfer, Gary M., Sung, Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381662/
https://ncbi.nlm.nih.gov/pubmed/27239033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.007
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares