Kinase-independent function of E-type cyclins in liver cancer

E-type cyclins (cyclins E1 and E2) are components of the core cell cycle machinery and are overexpressed in many human tumor types. E cyclins are thought to drive tumor cell proliferation by activating the cyclin-dependent kinase 2 (CDK2). The cyclin E1 gene represents the site of recurrent integrat...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Geng, Yan, Michowski, Wojciech, Chick, Joel M., Wang, Yaoyu E., Jecrois, M. Emmanuelle, Sweeney, Katharine E., Liu, Lijun, Han, Richard C., Ke, Nan, Zagozdzon, Agnieszka, Sicinska, Ewa, Bronson, Roderick T., Gygi, Steven P., Sicinski, Piotr
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798328/
https://ncbi.nlm.nih.gov/pubmed/29339491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711477115
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