Deletion of the p27(Kip1) gene restores normal development in cyclin D1-deficient mice

D-type cyclins (cyclins D1, D2, and D3) are key components of cell cycle machinery in mammalian cells. These proteins are believed to drive cell cycle progression by associating with their kinase partners, cyclin-dependent kinases, and by directing phosphorylation of critical cellular substrates. In...

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Bibliografiske detaljer
Main Authors: Geng, Yan, Yu, Qunyan, Sicinska, Ewa, Das, Manjusri, Bronson, Roderick T., Sicinski, Piotr
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14567/
https://ncbi.nlm.nih.gov/pubmed/11134518
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