Deletion of the p27(Kip1) gene restores normal development in cyclin D1-deficient mice

D-type cyclins (cyclins D1, D2, and D3) are key components of cell cycle machinery in mammalian cells. These proteins are believed to drive cell cycle progression by associating with their kinase partners, cyclin-dependent kinases, and by directing phosphorylation of critical cellular substrates. In...

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Main Authors: Geng, Yan, Yu, Qunyan, Sicinska, Ewa, Das, Manjusri, Bronson, Roderick T., Sicinski, Piotr
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC14567/
https://ncbi.nlm.nih.gov/pubmed/11134518
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