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Elevated Cyclin E Levels, Inactive Retinoblastoma Protein, and Suppression of the p27(KIP1) Inhibitor Characterize Early Development of Promyeloid Cells into Macrophages
Cyclin-dependent kinase inhibitors such as p27(KIP1) have recently been shown to lead to cellular differentiation by causing cell cycle arrest, but it is unknown whether similar events occur in differentiating promyeloid cells. Hematopoietic progenitor cells undergo lineage-restricted differentiatio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC84572/ https://ncbi.nlm.nih.gov/pubmed/10454569 |
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