Kinase-independent function of E-type cyclins in liver cancer

E-type cyclins (cyclins E1 and E2) are components of the core cell cycle machinery and are overexpressed in many human tumor types. E cyclins are thought to drive tumor cell proliferation by activating the cyclin-dependent kinase 2 (CDK2). The cyclin E1 gene represents the site of recurrent integrat...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Geng, Yan, Michowski, Wojciech, Chick, Joel M., Wang, Yaoyu E., Jecrois, M. Emmanuelle, Sweeney, Katharine E., Liu, Lijun, Han, Richard C., Ke, Nan, Zagozdzon, Agnieszka, Sicinska, Ewa, Bronson, Roderick T., Gygi, Steven P., Sicinski, Piotr
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798328/
https://ncbi.nlm.nih.gov/pubmed/29339491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711477115
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items