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Structural basis for molecular recognition of folic acid by folate receptors

Folate receptors (FRα, FRβ and FRγ) are cysteine-rich cell-surface glycoproteins that bind folate with high affinity to mediate cellular uptake of folate. Although expressed at very low levels in most tissues, folate receptors, especially FRα, are expressed at high levels in numerous cancers to meet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Chen, Chen, Ke, Jiyuan, Zhou, X Edward, Yi, Wei, Brunzelle, Joseph S., Li, Jun, Yong, Eu-Leong, Xu, H. Eric, Melcher, Karsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797940/
https://ncbi.nlm.nih.gov/pubmed/23851396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12327
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