Population Pharmacokinetic Modeling of a Desmopressin Oral Lyophilisate in Growing Piglets as a Model for the Pediatric Population

Desmopressin is used to treat primary nocturnal enuresis in children. Over the years, various formulations of desmopressin were commercialized of which the sublingual melt tablet is preferred in the pediatric population, despite the lack of full PK studies in this population. A full PK study was per...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Gasthuys, Elke, Vermeulen, An, Croubels, Siska, Millecam, Joske, Schauvliege, Stijn, van Bergen, Thomas, De Bruyne, Pauline, Vande Walle, Johan, Devreese, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797931/
https://ncbi.nlm.nih.gov/pubmed/29445339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00041
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