Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction

Disturbed intestinal epithelial barrier and mucosal micro-inflammation characterize irritable bowel syndrome (IBS). Despite intensive research demonstrating ovarian hormones modulation of IBS severity, there is still limited knowledge on the mechanisms underlying female predominance in this disorder...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Rodiño-Janeiro, Bruno K., Martínez, Cristina, Fortea, Marina, Lobo, Beatriz, Pigrau, Marc, Nieto, Adoración, González-Castro, Ana María, Salvo-Romero, Eloísa, Guagnozzi, Danila, Pardo-Camacho, Cristina, Iribarren, Cristina, Azpiroz, Fernando, Alonso-Cotoner, Carmen, Santos, Javier, Vicario, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797119/
https://ncbi.nlm.nih.gov/pubmed/29396473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20540-9
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak