Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

Corticotropin-releasing factor (CRF) has been identified in intestinal mucosal eosinophils and associated with psychological stress and gut dysfunction. Irritable bowel syndrome (IBS) is commonly characterized by altered intestinal motility, immune activation, and increased gut barrier permeability...

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Publicado no:Sci Rep
Main Authors: Salvo-Romero, Eloísa, Martínez, Cristina, Lobo, Beatriz, Rodiño-Janeiro, Bruno K., Pigrau, Marc, Sánchez-Chardi, Alejandro D., González-Castro, Ana M., Fortea, Marina, Pardo-Camacho, Cristina, Nieto, Adoración, Expósito, Elba, Guagnozzi, Danila, Rodríguez-Urrutia, Amanda, de Torres, Inés, Farré, Ricard, Azpiroz, Fernando, Alonso-Cotoner, Carmen, Santos, Javier, Vicario, María
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692489/
https://ncbi.nlm.nih.gov/pubmed/33244004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77176-x
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