Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

Corticotropin-releasing factor (CRF) has been identified in intestinal mucosal eosinophils and associated with psychological stress and gut dysfunction. Irritable bowel syndrome (IBS) is commonly characterized by altered intestinal motility, immune activation, and increased gut barrier permeability...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Salvo-Romero, Eloísa, Martínez, Cristina, Lobo, Beatriz, Rodiño-Janeiro, Bruno K., Pigrau, Marc, Sánchez-Chardi, Alejandro D., González-Castro, Ana M., Fortea, Marina, Pardo-Camacho, Cristina, Nieto, Adoración, Expósito, Elba, Guagnozzi, Danila, Rodríguez-Urrutia, Amanda, de Torres, Inés, Farré, Ricard, Azpiroz, Fernando, Alonso-Cotoner, Carmen, Santos, Javier, Vicario, María
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692489/
https://ncbi.nlm.nih.gov/pubmed/33244004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77176-x
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