Downregulation of mucosal mast cell activation and immune response in diarrhoea-irritable bowel syndrome by oral disodium cromoglycate: A pilot study

BACKGROUND AND GOAL: Diarrhoea-predominant irritable bowel syndrome (IBS-D) exhibits intestinal innate immune and mucosal mast cell (MC) activation. MC stabilisers have been shown to improve IBS symptoms but the mechanism is unclear. Our primary aim was to investigate the effect of oral disodium cro...

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Detalhes bibliográficos
Publicado no:United European Gastroenterol J
Main Authors: Lobo, Beatriz, Ramos, Laura, Martínez, Cristina, Guilarte, Mar, González-Castro, Ana M, Alonso-Cotoner, Carmen, Pigrau, Marc, de Torres, Inés, Rodiño-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina, Pardo-Camacho, Cristina, Guagnozzi, Danila, Azpiroz, Fernando, Santos, Javier, Vicario, María
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625876/
https://ncbi.nlm.nih.gov/pubmed/29026603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640617691690
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