Downregulation of mucosal mast cell activation and immune response in diarrhoea-irritable bowel syndrome by oral disodium cromoglycate: A pilot study

BACKGROUND AND GOAL: Diarrhoea-predominant irritable bowel syndrome (IBS-D) exhibits intestinal innate immune and mucosal mast cell (MC) activation. MC stabilisers have been shown to improve IBS symptoms but the mechanism is unclear. Our primary aim was to investigate the effect of oral disodium cro...

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Bibliographische Detailangaben
Veröffentlicht in:United European Gastroenterol J
Hauptverfasser: Lobo, Beatriz, Ramos, Laura, Martínez, Cristina, Guilarte, Mar, González-Castro, Ana M, Alonso-Cotoner, Carmen, Pigrau, Marc, de Torres, Inés, Rodiño-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina, Pardo-Camacho, Cristina, Guagnozzi, Danila, Azpiroz, Fernando, Santos, Javier, Vicario, María
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625876/
https://ncbi.nlm.nih.gov/pubmed/29026603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640617691690
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