Downregulation of mucosal mast cell activation and immune response in diarrhoea-irritable bowel syndrome by oral disodium cromoglycate: A pilot study

BACKGROUND AND GOAL: Diarrhoea-predominant irritable bowel syndrome (IBS-D) exhibits intestinal innate immune and mucosal mast cell (MC) activation. MC stabilisers have been shown to improve IBS symptoms but the mechanism is unclear. Our primary aim was to investigate the effect of oral disodium cro...

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Bibliografische gegevens
Gepubliceerd in:United European Gastroenterol J
Hoofdauteurs: Lobo, Beatriz, Ramos, Laura, Martínez, Cristina, Guilarte, Mar, González-Castro, Ana M, Alonso-Cotoner, Carmen, Pigrau, Marc, de Torres, Inés, Rodiño-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina, Pardo-Camacho, Cristina, Guagnozzi, Danila, Azpiroz, Fernando, Santos, Javier, Vicario, María
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2017
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625876/
https://ncbi.nlm.nih.gov/pubmed/29026603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640617691690
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