miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea

OBJECTIVE: Micro-RNAs (miRNAs) play a crucial role in controlling intestinal epithelial barrier function partly by modulating the expression of tight junction (TJ) proteins. We have previously shown differential messenger RNA (mRNA) expression correlated with ultrastructural abnormalities of the epi...

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Dades bibliogràfiques
Publicat a:Gut
Autors principals: Martínez, Cristina, Rodiño-Janeiro, Bruno K, Lobo, Beatriz, Stanifer, Megan L, Klaus, Bernd, Granzow, Martin, González-Castro, Ana M, Salvo-Romero, Eloisa, Alonso-Cotoner, Carmen, Pigrau, Marc, Roeth, Ralph, Rappold, Gudrun, Huber, Wolfgang, González-Silos, Rosa, Lorenzo, Justo, de Torres, Inés, Azpiroz, Fernando, Boulant, Steeve, Vicario, María, Niesler, Beate, Santos, Javier
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2017
Matèries:
Neurogastroenterology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561373/
https://ncbi.nlm.nih.gov/pubmed/28082316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-311477
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