TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

Although the mechanisms of Tumor necrosis factor alpha (TNF-α) on facilitating osteoclast differentiation and bone resorption is well known, the mechanisms behind the suppression of the osteoblast differentiation from mesenchymal stem cells (MSCs) are still poorly understood. In this study, we obser...

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Udgivet i:Oncotarget
Main Authors: Zuo, Chijian, Zhao, Xiaoying, Shi, Yu, Wu, Wen, Zhang, Ning, Xu, Jiake, Wang, Chuandong, Hu, Guoli, Zhang, Xiaoling
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797016/
https://ncbi.nlm.nih.gov/pubmed/29435145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23373
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