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Activation of NF-κB by Fluid Shear Stress, but not TNF-α, Requires Focal Adhesion Kinase in Osteoblasts
When bone is mechanically loaded fluid shear stress (FSS) is generated as a result of the movement of interstitial fluid across the membranes of osteoblasts and osteocytes. This external mechanical loading stimulates changes in the activity of cytoplasmic signaling molecules and alters gene expressi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891440/ https://ncbi.nlm.nih.gov/pubmed/20353839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2010.03.014 |
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