PURINERGIC SIGNALING IS REQUIRED FOR FLUID SHEAR STRESS-INDUCED NF-κB TRANSLOCATION IN OSTEOBLASTS

Fluid shear stress regulates gene expression in osteoblasts, in part by activation of the transcription factor NF-κB. We examined whether this process was under control of purinoceptor activation. MC3T3-E1 osteoblasts under static conditions expressed the NF-κB inhibitory protein IκBα and exhibited...

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Hauptverfasser: Genetos, Damian C., Karin, Norman J., Geist, Derik J., Donahue, Henry J., Duncan, Randall L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049820/
https://ncbi.nlm.nih.gov/pubmed/21237152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.01.007
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