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Fluid Shear-Induced ATP Secretion Mediates Prostaglandin Release in MC3T3-E1 Osteoblasts

ATP is rapidly released from osteoblasts in response to mechanical load. We examined the mechanisms involved in this release and established that shear-induced ATP release was mediated through vesicular fusion and was dependent on Ca(2+) entry into the cell via L-type voltage-sensitive Ca(2+) channe...

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Autors principals: Genetos, Damian C., Geist, Derik J., Dawei, Liu, Donahue, Henry J., Duncan, Randall L.
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929123/
https://ncbi.nlm.nih.gov/pubmed/15619668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.041009
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