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OSCILLATING FLUID FLOW ACTIVATION OF GAP JUNCTION HEMICHANNELS INDUCES ATP RELEASE FROM MLO-Y4 OSTEOCYTES

Mechanical loads are required for optimal bone mass. One mechanism whereby mechanical loads are transduced into localized cellular signals is strain-induced fluid flow through lacunae and canaliculi of bone. Gap junctions (GJ) between osteocytes and osteoblasts provides a mechanism whereby flow-indu...

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Autores principales: Genetos, Damian C., Kephart, Curtis J., Zhang, Yue, Yellowley, Clare E., Donahue, Henry J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929812/
https://ncbi.nlm.nih.gov/pubmed/17301958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21021
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