Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Xanthine oxidase and xanthine dehydrogenase have been implicated in producing myocardial damage following reperfusion of an occluded coronary artery. We investigated and compared the effect of febuxostat and allopurinol in an experimental model of ischemia-reperfusion (IR) injury with a focus on the...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Khan, Sana Irfan, Malhotra, Rajiv Kumar, Rani, Neha, Sahu, Anil Kumar, Tomar, Ameesha, Garg, Shanky, Nag, Tapas Chandra, Ray, Ruma, Ojha, Shreesh, Arya, Dharamvir Singh, Bhatia, Jagriti
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613710/
https://ncbi.nlm.nih.gov/pubmed/29138678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8095825
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