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Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Xanthine oxidase and xanthine dehydrogenase have been implicated in producing myocardial damage following reperfusion of an occluded coronary artery. We investigated and compared the effect of febuxostat and allopurinol in an experimental model of ischemia-reperfusion (IR) injury with a focus on the...

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書目詳細資料
發表在:Oxid Med Cell Longev
Main Authors: Khan, Sana Irfan, Malhotra, Rajiv Kumar, Rani, Neha, Sahu, Anil Kumar, Tomar, Ameesha, Garg, Shanky, Nag, Tapas Chandra, Ray, Ruma, Ojha, Shreesh, Arya, Dharamvir Singh, Bhatia, Jagriti
格式: Artigo
語言:Inglês
出版: Hindawi 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613710/
https://ncbi.nlm.nih.gov/pubmed/29138678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8095825
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