Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Xanthine oxidase and xanthine dehydrogenase have been implicated in producing myocardial damage following reperfusion of an occluded coronary artery. We investigated and compared the effect of febuxostat and allopurinol in an experimental model of ischemia-reperfusion (IR) injury with a focus on the...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oxid Med Cell Longev
Huvudupphovsmän: Khan, Sana Irfan, Malhotra, Rajiv Kumar, Rani, Neha, Sahu, Anil Kumar, Tomar, Ameesha, Garg, Shanky, Nag, Tapas Chandra, Ray, Ruma, Ojha, Shreesh, Arya, Dharamvir Singh, Bhatia, Jagriti
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613710/
https://ncbi.nlm.nih.gov/pubmed/29138678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8095825
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