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RNA-dependent RNA targeting by CRISPR-Cas9
Double-stranded DNA (dsDNA) binding and cleavage by Cas9 is a hallmark of type II CRISPR-Cas bacterial adaptive immunity. All known Cas9 enzymes are thought to recognize DNA exclusively as a natural substrate, providing protection against DNA phage and plasmids. Here, we show that Cas9 enzymes from...
Uloženo v:
| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796797/ https://ncbi.nlm.nih.gov/pubmed/29303478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32724 |
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