An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells

Chromatin regulators control cellular differentiation by orchestrating dynamic developmental gene expression programs, and hence, malfunctions in the regulation of chromatin state contribute to both developmental disorders and disease state. Mll4 (Kmt2d), a member of the COMPASS (COMplex of Proteins...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Cao, Kaixiang, Collings, Clayton K., Morgan, Marc A., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Smith, Edwin R., Shilatifard, Ali
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796793/
https://ncbi.nlm.nih.gov/pubmed/29404406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aap8747
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge