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ФC31 Integrase-Mediated Isolation and Characterization of Novel Safe Harbors for Transgene Expression in the Pig Genome

Programmable nucleases have allowed the rapid development of gene editing and transgenics, but the technology still suffers from the lack of predefined genetic loci for reliable transgene expression and maintenance. To address this issue, we used ФC31 integrase to navigate the porcine genome and ide...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Bi, Yanzhen, Hua, Zaidong, Ren, Hongyan, Zhang, Liping, Xiao, Hongwei, Liu, Ximei, Hua, Wenjun, Mei, Shuqi, Molenaar, Adrian, Laible, Götz, Zheng, Xinmin
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796098/
https://ncbi.nlm.nih.gov/pubmed/29300364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010149
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