Pseudo attP sites in favor of transgene integration and expression in cultured porcine cells identified by streptomyces phage phiC31 integrase

Phage PhiC31 integrase integrates attB-containing plasmid into pseudo attP site in eukaryotic genomes in a unidirectional site-specific manner and maintains robust transgene expression. Few studies, however, explore its potential in livestock. This study aims to discover the molecular basis of PhiC3...

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Hauptverfasser: Bi, Yanzhen, Liu, Ximei, Zhang, Long, Shao, Changwei, Ma, Zhuo, Hua, Zaidong, Zhang, Liping, Li, Li, Hua, Wenjun, Xiao, Hongwei, Wei, Qingxin, Zheng, Xinmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844521/
https://ncbi.nlm.nih.gov/pubmed/24010979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-14-20
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