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Serine integrase attP binding and specificity

Serine integrases catalyze the site-specific insertion of viral DNA into a host’s genome. The minimal requirements and irreversible nature of this integration reaction has led to the use of serine integrases in applications ranging from bacterial memory storage devices to gene therapy. Our understan...

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Dades bibliogràfiques
Publicat a:J Mol Biol
Autors principals: Li, Huiguang, Sharp, Robert, Rutherford, Karen, Gupta, Kushol, Duyne, Gregory D. Van
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339855/
https://ncbi.nlm.nih.gov/pubmed/30227134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.09.007
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