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Screening of potential pseudo att sites of Streptomyces phage ΦC31 integrase in the human genome

AIM: ΦC31 integrase mediates site-specific recombination between two short sequences, attP and attB, in phage and bacterial genomes, which is a promising tool in gene regulation-based therapy since the zinc finger structure is probably the DNA recognizing domain that can further be engineered. The a...

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Detalhes bibliográficos
Main Authors: Hu, Zhi-peng, Chen, Lu-sheng, Jia, Cai-yan, Zhu, Huan-zhang, Wang, Wei, Zhong, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002784/
https://ncbi.nlm.nih.gov/pubmed/23416928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.173
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