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Adjusting the attB Site in Donor Plasmid Improves the Efficiency of ΦC31 Integrase System

ΦC31 integrase, a site-specific recombinase, can catalyze integration of circular DNA bearing attB site into pseudo attP sites in mammalian genomes. However, the integration efficiency mediated by integrase is relatively low. Our study centered on the investigation of the impact of the position, ori...

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Detalhes bibliográficos
Main Authors: Xie, Fei, Ma, Qingwen, Jiang, Shizhong, Ren, Zhaorui, Wang, Juan, Huang, Shuzhen, Zeng, Fanyi, Zeng, Yitao
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391497/
https://ncbi.nlm.nih.gov/pubmed/22489575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1590
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