Adjusting the attB Site in Donor Plasmid Improves the Efficiency of ΦC31 Integrase System

ΦC31 integrase, a site-specific recombinase, can catalyze integration of circular DNA bearing attB site into pseudo attP sites in mammalian genomes. However, the integration efficiency mediated by integrase is relatively low. Our study centered on the investigation of the impact of the position, ori...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Xie, Fei, Ma, Qingwen, Jiang, Shizhong, Ren, Zhaorui, Wang, Juan, Huang, Shuzhen, Zeng, Fanyi, Zeng, Yitao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2012
Ämnen:
Original Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391497/
https://ncbi.nlm.nih.gov/pubmed/22489575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1590
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk