載入...
Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection
DNA double-strand break repair by homologous recombination is initiated by DNA end resection, which is commenced by the Mre11–Rad50–Xrs2 complex and Sae2 in yeast. Here we report that the nonhomologous end joining factor Ku limits the exonuclease activity of Mre11 and promotes its endonuclease to cl...
Na minha lista:
| 發表在: | Genes Dev |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5795779/ https://ncbi.nlm.nih.gov/pubmed/29321179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.308254.117 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
載入...