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Relationship of DNA degradation by Saccharomyces cerevisiae Exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection

Homologous recombination is a major pathway for repair of DNA double-strand breaks. This repair process is initiated by resection of the 5′-terminated strand at the break site. In yeast, resection is carried out by three nucleolytic complexes: Mre11-Rad50-Xrs2, which functions at the initial step an...

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Detalhes bibliográficos
Main Authors: Cannavo, Elda, Cejka, Petr, Kowalczykowski, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645542/
https://ncbi.nlm.nih.gov/pubmed/23589858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305166110
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