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Relationship of DNA degradation by Saccharomyces cerevisiae Exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection
Homologous recombination is a major pathway for repair of DNA double-strand breaks. This repair process is initiated by resection of the 5′-terminated strand at the break site. In yeast, resection is carried out by three nucleolytic complexes: Mre11-Rad50-Xrs2, which functions at the initial step an...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645542/ https://ncbi.nlm.nih.gov/pubmed/23589858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305166110 |
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