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Xrs2 dependent and independent functions of the Mre11-Rad50 complex
The Mre11-Rad50-Xrs2/Nbs1 (MRX/N) complex orchestrates the cellular response to DSBs through its structural, enzymatic and signaling roles. Xrs2/Nbs1 is essential for nuclear translocation of Mre11, but its role as a component of the complex is not well defined. Here we demonstrate that nuclear loca...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123801/ https://ncbi.nlm.nih.gov/pubmed/27746018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.09.011 |
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