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Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals

BACKGROUND AND OBJECTIVES: Maximum plasma concentration of biopharmaceuticals sometimes occurs long after completion of intravenous infusion. The objective of this research was to study the hypothetical adsorption of biopharmaceuticals to endothelium and infusion material, which may theoretically ex...

詳細記述

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書誌詳細
出版年:Eur J Drug Metab Pharmacokinet
主要な著者: Reijers, Joannes A. A., Dane, Martijn J. C., van Zonneveld, Anton Jan, Burggraaf, Jacobus, Moerland, Matthijs
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794845/
https://ncbi.nlm.nih.gov/pubmed/28795390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-017-0430-1
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