Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals

BACKGROUND AND OBJECTIVES: Maximum plasma concentration of biopharmaceuticals sometimes occurs long after completion of intravenous infusion. The objective of this research was to study the hypothetical adsorption of biopharmaceuticals to endothelium and infusion material, which may theoretically ex...

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Publicat a:Eur J Drug Metab Pharmacokinet
Autors principals: Reijers, Joannes A. A., Dane, Martijn J. C., van Zonneveld, Anton Jan, Burggraaf, Jacobus, Moerland, Matthijs
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2017
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794845/
https://ncbi.nlm.nih.gov/pubmed/28795390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-017-0430-1
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