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Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals

BACKGROUND AND OBJECTIVES: Maximum plasma concentration of biopharmaceuticals sometimes occurs long after completion of intravenous infusion. The objective of this research was to study the hypothetical adsorption of biopharmaceuticals to endothelium and infusion material, which may theoretically ex...

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Detalhes bibliográficos
Publicado no:Eur J Drug Metab Pharmacokinet
Principais autores: Reijers, Joannes A. A., Dane, Martijn J. C., van Zonneveld, Anton Jan, Burggraaf, Jacobus, Moerland, Matthijs
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794845/
https://ncbi.nlm.nih.gov/pubmed/28795390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-017-0430-1
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