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Adverse immunostimulation caused by impurities: The dark side of biopharmaceuticals

Drug safety is an important issue, especially in the experimental phases of development. Adverse immunostimulation (AI) is sometimes encountered following treatment with biopharmaceuticals, which can be life‐threatening if it results in a severe systemic inflammatory reaction. Biopharmaceuticals tha...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Reijers, Joannes A. A., Malone, Karen E., Bajramovic, Jeffrey J., Verbeek, Richard, Burggraaf, Jacobus, Moerland, Matthijs
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595286/
https://ncbi.nlm.nih.gov/pubmed/30920013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13938
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