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Remarkable Pharmacokinetics of Monoclonal Antibodies: A Quest for an Explanation
Monoclonal antibodies (MAbs) usually display slow and limited distribution with combined linear and non-linear elimination mechanisms. While studying individual pharmacokinetic profiles, it was noticed that MAb plasma concentration can vary abruptly over time, with one or more increases after the ti...
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| Publicado no: | Clin Pharmacokinet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563346/ https://ncbi.nlm.nih.gov/pubmed/28000101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0497-x |
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