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The role of purified Clostridium difficile glucosylating toxins in disease pathogenesis utilizing a murine cecum injection model

Most pathogenic Clostridium difficile produce two major exotoxins TcdA and TcdB, in the absence of which the bacterium is non-pathogenic. While it is important to investigate the role of each toxin in the pathogenesis of C. difficile infection (CDI) using isogenic strains, it is impossible to precis...

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Detalhes bibliográficos
Publicado no:Anaerobe
Main Authors: Zhang, Yongrong, Yang, Zhiyong, Gao, Si, Hamza, Therwa, Yfantis, Harris G., Lipsky, Michael, Feng, Hanping
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792825/
https://ncbi.nlm.nih.gov/pubmed/29031928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.anaerobe.2017.10.006
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