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Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides

Clostridium difficile toxin A and B (TcdA and TcdB) are the major virulence factors of the bacterium, both of which consist of two enzymatic domains: an effector glucosyltransferase domain (GTD) and a cysteine protease domain (CPD) responsible for autocleavage and release of GTD. Although the CPDs f...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Zhang, Yongrong, Hamza, Therwa, Gao, Si, Feng, Hanping
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426850/
https://ncbi.nlm.nih.gov/pubmed/25725153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.095
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