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Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides
Clostridium difficile toxin A and B (TcdA and TcdB) are the major virulence factors of the bacterium, both of which consist of two enzymatic domains: an effector glucosyltransferase domain (GTD) and a cysteine protease domain (CPD) responsible for autocleavage and release of GTD. Although the CPDs f...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426850/ https://ncbi.nlm.nih.gov/pubmed/25725153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.095 |
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