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Defective mutations within the translocation domain of Clostridium difficile toxin B impair disease pathogenesis

The Clostridium difficile toxin B is one of the main virulence factors and plays an important role in the pathogenesis of C. difficile infection (CDI). We recently revealed crucial residues in the translocation domain of TcdB for the pore formation and toxin translocation. In this study, we investig...

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Detaylı Bibliyografya
Yayımlandı:Pathog Dis
Asıl Yazarlar: Hamza, Therwa, Zhang, Zhifen, Melnyk, Roman A., Feng, Hanping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882082/
https://ncbi.nlm.nih.gov/pubmed/26507679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv098
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