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Defective mutations within the translocation domain of Clostridium difficile toxin B impair disease pathogenesis
The Clostridium difficile toxin B is one of the main virulence factors and plays an important role in the pathogenesis of C. difficile infection (CDI). We recently revealed crucial residues in the translocation domain of TcdB for the pore formation and toxin translocation. In this study, we investig...
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| Publicado no: | Pathog Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882082/ https://ncbi.nlm.nih.gov/pubmed/26507679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv098 |
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