EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation

BACKGROUND: Amplification of the epidermal growth factor receptor (EGFR) and its mutant EGFRvIII are among the most common genetic alterations in glioblastoma (GBM), the most frequent and most aggressive primary brain tumor. METHODS: In the present work, we analyzed the clonal evolution of these maj...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Eskilsson, Eskil, Rosland, Gro V., Talasila, Krishna M., Knappskog, Stian, Keunen, Olivier, Sottoriva, Andrea, Foerster, Sarah, Solecki, Gergely, Taxt, Torfinn, Jirik, Radovan, Fritah, Sabrina, Harter, Patrick N., Välk, Kristjan, Al Hossain, Jubayer, Joseph, Justin V., Jahedi, Roza, Saed, Halala S., Piccirillo, Sara G., Spiteri, Inma, Leiss, Lina, Euskirchen, Philipp, Graziani, Grazia, Daubon, Thomas, Lund-Johansen, Morten, Enger, Per Øyvind, Winkler, Frank, Ritter, Christoph A., Niclou, Simone P., Watts, Colin, Bjerkvig, Rolf, Miletic, Hrvoje
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791772/
https://ncbi.nlm.nih.gov/pubmed/27286795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados