EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation

BACKGROUND: Amplification of the epidermal growth factor receptor (EGFR) and its mutant EGFRvIII are among the most common genetic alterations in glioblastoma (GBM), the most frequent and most aggressive primary brain tumor. METHODS: In the present work, we analyzed the clonal evolution of these maj...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Neuro Oncol
Main Authors: Eskilsson, Eskil, Rosland, Gro V., Talasila, Krishna M., Knappskog, Stian, Keunen, Olivier, Sottoriva, Andrea, Foerster, Sarah, Solecki, Gergely, Taxt, Torfinn, Jirik, Radovan, Fritah, Sabrina, Harter, Patrick N., Välk, Kristjan, Al Hossain, Jubayer, Joseph, Justin V., Jahedi, Roza, Saed, Halala S., Piccirillo, Sara G., Spiteri, Inma, Leiss, Lina, Euskirchen, Philipp, Graziani, Grazia, Daubon, Thomas, Lund-Johansen, Morten, Enger, Per Øyvind, Winkler, Frank, Ritter, Christoph A., Niclou, Simone P., Watts, Colin, Bjerkvig, Rolf, Miletic, Hrvoje
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Basic and Translational Investigation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791772/
https://ncbi.nlm.nih.gov/pubmed/27286795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now113
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla