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Exogenous insulin infusion can decrease atherosclerosis in diabetic rodents by improving lipids, inflammation, and endothelial function
OBJECTIVE: To evaluate whether exogenously-induced hyperinsulinemia may increase the development of atherosclerosis. APPROACH & RESULTS: Hyperinsulinemia, induced by exogenous insulin implantation in high fat fed (60% fat HFD) ApoE(−/−) mice, exhibited insulin resistance, hyperglycemia and hyper...
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| Yayımlandı: | Arterioscler Thromb Vasc Biol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791542/ https://ncbi.nlm.nih.gov/pubmed/29162603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310291 |
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