High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes

BACKGROUND: Cardiovascular disease (CVD) is a major cause of mortality in type 1 diabetes (T1D). A pro-calcific drift of circulating monocytes has been linked to vascular calcification and is marked by the surface expression of osteocalcin (OCN). We studied OCN+ monocytes in a unique population with...

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Veröffentlicht in:Cardiovasc Diabetol
Hauptverfasser: Maddaloni, Ernesto, Xia, Yu, Park, Kyoungmin, D’Eon, Stephanie, Tinsley, Liane J., St-Louis, Ronald, Khamaisi, Mogher, Li, Qian, King, George L., Keenan, Hillary A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602856/
https://ncbi.nlm.nih.gov/pubmed/28915881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0599-2
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