Insulin decreases atherosclerosis by inducing endothelin receptor B expression

Endothelial cell (EC) insulin resistance and dysfunction, caused by diabetes, accelerates atherosclerosis. It is unknown whether specifically enhancing EC-targeted insulin action can decrease atherosclerosis in diabetes. Accordingly, overexpressing insulin receptor substrate-1 (IRS1) in the endothel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Park, Kyoungmin, Mima, Akira, Li, Qian, Rask-Madsen, Christian, He, Pingnian, Mizutani, Koji, Katagiri, Sayaka, Maeda, Yasutaka, Wu, I-Hsien, Khamaisi, Mogher, Preil, Simone Rordam, Maddaloni, Ernesto, Sørensen, Ditte, Rasmussen, Lars Melholt, Huang, Paul L., King, George L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869734/
https://ncbi.nlm.nih.gov/pubmed/27200419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86574
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