Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections

Coronaviruses recently emerged as major human pathogens causing outbreaks of severe acute respiratory syndrome and Middle East respiratory syndrome. They utilize the spike (S) glycoprotein anchored in the viral envelope to mediate host attachment and fusion of the viral and cellular membranes to ini...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Xiong, Xiaoli, Tortorici, M. Alejandra, Snijder, Joost, Yoshioka, Craig, Walls, Alexandra C., Li, Wentao, McGuire, Andrew T., Rey, Félix A., Bosch, Berend-Jan, Veesler, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790929/
https://ncbi.nlm.nih.gov/pubmed/29093093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01628-17
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