Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

The emergence of SARS-CoV-2 has resulted in >90,000 infections and >3,000 deaths. Coronavirus spike (S) glycoproteins promote entry into cells and are the main target of antibodies. We show that SARS-CoV-2 S uses ACE2 to enter cells and that the receptor-binding domains of SARS-CoV-2 S and SAR...

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Publicado no:Cell
Main Authors: Walls, Alexandra C., Park, Young-Jun, Tortorici, M. Alejandra, Wall, Abigail, McGuire, Andrew T., Veesler, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102599/
https://ncbi.nlm.nih.gov/pubmed/32155444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.02.058
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